New Research - Keto Trial Promises New Treatment Option in Bipolar Disorder
New Research - Keto Trial Promises New Treatment Option in Bipolar Disorder




We are a nonprofit transforming the study and treatment of mental disorders by exploring the connection between metabolism and brain health.
We are a nonprofit transforming the study and treatment of mental disorders by exploring the connection between metabolism and brain health.
We are a nonprofit transforming the study and treatment of mental disorders by exploring the connection between metabolism and brain health.
We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.
The Metabolic Mind Story


Mental Health is Metabolic Health
Mental Health is Metabolic Health
Mental Health is Metabolic Health
Decades of scientific evidence suggest that mental illness is rooted in systemic metabolic dysfunction affecting the brain. Ketogenic therapy and other metabolic strategies are emerging as promising new treatments for psychiatric disorders.
Decades of scientific evidence suggest that mental illness is rooted in systemic metabolic dysfunction affecting the brain. Ketogenic therapy and other metabolic strategies are emerging as promising new treatments for psychiatric disorders.
Initiative of Baszucki Group
Initiative of Baszucki Group
Initiative of Baszucki Group
Our founders personally understand the challenges of a mental health crisis as well as the life-restoring impact of successful interventions. They are dedicated to advancing the study of neurometabolism and ketogenic therapies to give hope to families like theirs.
Our founders personally understand the challenges of a mental health crisis as well as the life-restoring impact of successful interventions. They are dedicated to advancing the study of neurometabolism and ketogenic therapies to give hope to families like theirs.




NPR: Patients say keto helps with their mental illness. Science is racing to understand why
NPR: Patients say keto helps with their mental illness. Science is racing to understand why
NPR: Patients say keto helps with their mental illness. Science is racing to understand why



Iain Campbell, a researcher in Scotland, has lived with bipolar disorder since he was young. After trying the ketogenic diet, he discovered profound improvements in his symptoms — and now wants to learn if it can do the same for others.
Iain Campbell, a researcher in Scotland, has lived with bipolar disorder since he was young. After trying the ketogenic diet, he discovered profound improvements in his symptoms — and now wants to learn if it can do the same for others.
NPR Article
Fueling Mental Health
Fueling Mental Health
Fueling Mental Health
Uncovering the foundational connection between metabolism and mental health.
Uncovering the foundational connection between metabolism and mental health.



Don't Call it Bipolar Disorder with Hannah Warren
Don't Call it Bipolar Disorder with Hannah Warren
Hannah Warren used metabolic therapies like fasting, ketogenic diet, exercise, and meditation to send her bipolar disorder into remission. Now she raises awareness of effective treatment options for neurometabolic dysfunction to help others.



Brain Energy, Mitochondria, and Mental Health
Brain Energy, Mitochondria, and Mental Health
Harvard psychiatrist Dr. Chris Palmer has developed a cohesive theory characterizing mental illnesses as rooted in mitochondrial and metabolic dysfunction. His approach is transforming psychiatry.



Keto for Brain Health - A Dramatic Personal Journey
Keto for Brain Health - A Dramatic Personal Journey
Suzi was born with Down syndrome, and lived a full, happy life until her 40’s, when early dementia set in. Her mother, Mary, was desperate for answers before stumbling upon nutritional ketosis, which gave Suzi her life back.
Metabolism and Your Mental Wellbeing.
Metabolism and Your Mental Wellbeing.
Metabolism and Your Mental Wellbeing.
The facts.
The facts.
The facts.
Photo Credit: John Howland, M.D., professor of pediatrics at the Johns Hopkins University School of Medicine
Photo Credit: John Howland, M.D., professor of pediatrics at the Johns Hopkins University School of Medicine



Since the 1920s, a therapeutic ketogenic diet has been used to successfully treat epilepsy in children and adults.
Since the 1920s, a therapeutic ketogenic diet has been used to successfully treat epilepsy in children and adults.
Since the 1920s, a therapeutic ketogenic diet has been used to successfully treat epilepsy in children and adults.
This offers a big clue as to how metabolism impacts brain function–and how to fix it when it’s impaired.
Today people are using ketogenic therapy to find relief from dozens of other brain disorders, from Alzheimer’s to bipolar disorder to schizophrenia.
This offers a big clue as to how metabolism impacts brain function–and how to fix it when it’s impaired.
Today people are using ketogenic therapy to find relief from dozens of other brain disorders, from Alzheimer’s to bipolar disorder to schizophrenia.
This offers a big clue as to how metabolism impacts brain function–and how to fix it when it’s impaired.
Today people are using ketogenic therapy to find relief from dozens of other brain disorders, from Alzheimer’s to bipolar disorder to schizophrenia.



An evidence-based treatment for the brain
An evidence-based treatment for the brain
More than a dozen current clinical trials are extending the evidence for therapeutic ketosis from the field of neurology to the field of psychiatry.
More than a dozen current clinical trials are extending the evidence for therapeutic ketosis from the field of neurology to the field of psychiatry.



Improved brain health
Improved brain health
Neuroscience shows us that brain metabolism is impaired in people with mental disorders, and that improving it reduces symptoms.
Neuroscience shows us that brain metabolism is impaired in people with mental disorders, and that improving it reduces symptoms.
Neuroscience shows us that brain metabolism is impaired in people with mental disorders, and that improving it reduces symptoms.



More than just a diet
More than just a diet
Ketogenic diets aren’t just for weight loss. For many people, they can be a cornerstone of both metabolic and mental health.
Ketogenic diets aren’t just for weight loss. For many people, they can be a cornerstone of both metabolic and mental health.



Metabolic psychiatry
Metabolic psychiatry
A new field is rapidly emerging to assess and treat neurometabolic dysfunction to improve mental health.
A new field is rapidly emerging to assess and treat neurometabolic dysfunction to improve mental health.
“If we hadn’t come to understand that our son’s 'mental illness' was caused by disordered brain metabolism, he’d still be suffering.”
“If we hadn’t come to understand that our son’s 'mental illness' was caused by disordered brain metabolism, he’d still be suffering.”
“If we hadn’t come to understand that our son’s 'mental illness' was caused by disordered brain metabolism, he’d still be suffering.”

Jan Ellison Baszucki
Jan Ellison Baszucki
Founder
Founder

A Paradigm Shift
A Paradigm Shift
A Paradigm Shift
Conventional psychiatric treatment typically relies almost entirely on medications to keep symptoms under control. Talk therapy is often prescribed as an adjunctive treatment, but the root causes of mental illness, as well as the lifestyle changes that can lead to healing, are often left out of treatment paradigms.
Metabolic psychiatry seeks to flip treatment for mental illness on its head, putting therapeutic nutrition, circadian rhythm management, and movement as the foundation of recovery and wellness.
Conventional psychiatric treatment typically relies almost entirely on medications to keep symptoms under control. Talk therapy is often prescribed as an adjunctive treatment, but the root causes of mental illness, as well as the lifestyle changes that can lead to healing, are often left out of treatment paradigms.
Metabolic psychiatry seeks to flip treatment for mental illness on its head, putting therapeutic nutrition, circadian rhythm management, and movement as the foundation of recovery and wellness.



Metabolic Psychiatry: A Paradigm Shift in Psychiatric Treatment
Metabolic Psychiatry: A Paradigm Shift in Psychiatric Treatment
Metabolic Psychiatry: A Paradigm Shift in Psychiatric Treatment
Learn From Experts by Experience
Learn From Experts by Experience
Learn From Experts by Experience
A growing community is finding healing with metabolic therapies.
A growing community is finding healing with metabolic therapies.
A growing community is finding healing with metabolic therapies.




Changing Clinical Practice
Changing Clinical Practice
Changing Clinical Practice
Increasing numbers of clinicians are prescribing metabolic therapies to complement or even replace traditional psychiatric interventions.
Increasing numbers of clinicians are prescribing metabolic therapies to complement or even replace traditional psychiatric interventions.
Increasing numbers of clinicians are prescribing metabolic therapies to complement or even replace traditional psychiatric interventions.
Learn More
Brain Bioenergetics
Brain Bioenergetics
Brain Bioenergetics
The field of metabolic neuroscience is uncovering the connections between mitochondria, metabolism, and the brain.
The field of metabolic neuroscience is uncovering the connections between mitochondria, metabolism, and the brain.
The field of metabolic neuroscience is uncovering the connections between mitochondria, metabolism, and the brain.
Learn More


Metabolic Mind on YouTube
Hosted by Dr. Bret Scher, your go-to resource for up-to-date science, news, and personal stories in metabolic psychiatry.
Metabolic Mind YouTube Channel
Metabolic Mind
on YouTube
Hosted by Dr. Bret Scher, your go-to resource for up-to-date science, news, and personal stories in metabolic psychiatry.
Metabolic Mind YouTube Channel
Metabolic Mind
on YouTube
Hosted by Dr. Bret Scher, your go-to resource for up-to-date science, news, and personal stories in metabolic psychiatry.
Metabolic Mind YouTube Channel
The Metabolic Mind Blog:
Fueling Mental Health
The Metabolic Mind Blog:
Fueling Mental Health
Perspectives on the science and practice of metabolic therapies for mental health.
Perspectives on the science and practice of metabolic therapies for mental health.
Perspectives on the science and practice of metabolic therapies for mental health.



Ketogenic Diet Study Offers Hope for a New Treatment for Bipolar Disorder
Ketogenic Diet Study Offers Hope for a New Treatment for Bipolar Disorder
Ketogenic Diet Study Offers Hope for a New Treatment for Bipolar Disorder
Insights from Dr. Iain Campbell’s Research
Read More
Bret Scher, MD, FACC
Bret Scher, MD, FACC
Bret Scher, MD, FACC



Keto for Mental Health: Metabolic Mind's free THINK+SMART Tool
Keto for Mental Health: Metabolic Mind's free THINK+SMART Tool
Keto for Mental Health: Metabolic Mind's free THINK+SMART Tool
A Letter From Metabolic Mind's Founder
Read More
Jan Ellison Baszucki
Jan Ellison Baszucki
Jan Ellison Baszucki
A Metabolic Awakening: Reframing Psychosis from Breakdown to Breakthrough
A Metabolic Awakening: Reframing Psychosis from Breakdown to Breakthrough
A Metabolic Awakening: Reframing Psychosis from Breakdown to Breakthrough
Psychosis, like dreams, is an altered reality—vivid, surreal, and immersive. With metabolic healing, I process its lessons with clarity instead of fearing relapse.
Psychosis, like dreams, is an altered reality—vivid, surreal, and immersive. With metabolic healing, I process its lessons with clarity instead of fearing relapse.
Psychosis, like dreams, is an altered reality—vivid, surreal, and immersive. With metabolic healing, I process its lessons with clarity instead of fearing relapse.
Read More
Hannah Warren
Hannah Warren
Hannah Warren



Angels on Water Skis: My Descent into Mania & How I Regained & Maintain My Sanity
Angels on Water Skis: My Descent into Mania & How I Regained & Maintain My Sanity
Angels on Water Skis: My Descent into Mania & How I Regained & Maintain My Sanity
My journey from psychosis to remission: How I restored my brain energy.
My journey from psychosis to remission: How I restored my brain energy.
My journey from psychosis to remission: How I restored my brain energy.
Read More
Hannah Warren
Hannah Warren
Hannah Warren



Resources
Resources
Metabolic Mind is where families, clinicians, scientists, and advocates both learn and share experiences about the use of metabolic strategies for brain health.
Metabolic Mind is where families, clinicians, scientists, and advocates both learn and share experiences about the use of metabolic strategies for brain health.
Metabolic Mind is where families, clinicians, scientists, and advocates both learn and share experiences about the use of metabolic strategies for brain health.



Families and Peers
Families and Peers
Learn how you or your loved ones can adopt metabolic and ketogenic therapies to treat a mental disorder.
Learn how you or your loved ones can adopt metabolic and ketogenic therapies to treat a mental disorder.
Family and Peer Resources



Clinician Support
Clinician Support
Physicians, dieticians, therapists, and coaches are improving psychiatric care by addressing metabolic dysfunction.
Clinician Support



Research
Research
A growing number of basic, translational, and clinical studies link brain function to metabolism, including keto diet trials.
A growing number of basic, translational, and clinical studies link brain function to metabolism, including keto diet trials.
Research
Sign up for the Metabolic Mind Newsletter
We’ll keep you up-to-date with the most essential new videos, blogs, scientific papers, and news.
Sign up for the Metabolic Mind Newsletter
We’ll keep you up-to-date with the most essential new videos, blogs, scientific papers, and news.
Meet the Harvard and Stanford physicians at the Vanguard of Metabolic Psychiatry
Meet the Harvard and Stanford physicians at the Vanguard of Metabolic Psychiatry
Meet the Harvard and Stanford physicians at the Vanguard of Metabolic Psychiatry

Dr. Chris Palmer
“Mental disorders are metabolic disorders of the brain. I’ve seen patients’ lives transformed by metabolic therapies like the ketogenic diet, an evidence-based treatment for epilepsy.”
“Mental disorders are metabolic disorders of the brain. I’ve seen patients’ lives transformed by metabolic therapies like the ketogenic diet, an evidence-based treatment for epilepsy.”

Dr. Shebani Sethi
“Growing research points to a connection between mental illness and dysfunctional brain metabolism. Treating these dysfunctions can improve quality of life for many people."
“Growing research points to a connection between mental illness and dysfunctional brain metabolism. Treating these dysfunctions can improve quality of life for many people."

Dr. Georgia Ede
“There is nothing you can do to change the genes you were born with or the childhood you experienced, but you can change your diet–and changing your diet can change your mind.“
“There is nothing you can do to change the genes you were born with or the childhood you experienced, but you can change your diet–and changing your diet can change your mind."
From the Newsroom
From the Newsroom
What’s new in the world of metabolism and mental health.
What’s new in the world of metabolism and mental health.

Mar 11, 2025
Baszucki Group Announces Two Research Initiatives for Youth with Bipolar
Baszucki Group today announced the launch of two new initiatives across multiple sites exploring the effectiveness of ketogenic therapy for children and adolescents with bipolar disorder. The participating groups include a family resource center and four academic research institutions offering specialty programs devoted to treating serious mental illness in children and adolescents. These projects aim to develop ketogenic therapy programs and establish pilot data to fuel future randomized control trials and support programs in a youth population.
Baszucki Group today announced the launch of two new initiatives across multiple sites exploring the effectiveness of ketogenic therapy for children and adolescents with bipolar disorder. The participating groups include a family resource center and four academic research institutions offering specialty programs devoted to treating serious mental illness in children and adolescents. These projects aim to develop ketogenic therapy programs and establish pilot data to fuel future randomized control trials and support programs in a youth population.
Baszucki Group today announced the launch of two new initiatives across multiple sites exploring the effectiveness of ketogenic therapy for children and adolescents with bipolar disorder. The participating groups include a family resource center and four academic research institutions offering specialty programs devoted to treating serious mental illness in children and adolescents. These projects aim to develop ketogenic therapy programs and establish pilot data to fuel future randomized control trials and support programs in a youth population.

Mar 4, 2025
Precision Nutrition Takes Center Stage at Mayo Clinic in New Ketogenic Therapy Trial and Service
$3.3 million gift from Baszucki Group fuels transformative bipolar disorder research and precision nutrition clinical service.
$3.3 million gift from Baszucki Group fuels transformative bipolar disorder research and precision nutrition clinical service.
$3.3 million gift from Baszucki Group fuels transformative bipolar disorder research and precision nutrition clinical service.

Feb 25, 2025
New Bipolar Disorder Study Shows that a Ketogenic Diet Leads to Mental and Physical Health Benefits
“For the first time in years, I felt like my brain was finally running on the right fuel,” said one of the participants in a new pilot study on a ketogenic diet in bipolar disorder. Published today in BJPsych Open, the study is the first to use neuroimaging to demonstrate that a ketogenic diet may improve brain metabolism in individuals with a bipolar disorder diagnosis.
“For the first time in years, I felt like my brain was finally running on the right fuel,” said one of the participants in a new pilot study on a ketogenic diet in bipolar disorder. Published today in BJPsych Open, the study is the first to use neuroimaging to demonstrate that a ketogenic diet may improve brain metabolism in individuals with a bipolar disorder diagnosis.
“For the first time in years, I felt like my brain was finally running on the right fuel,” said one of the participants in a new pilot study on a ketogenic diet in bipolar disorder. Published today in BJPsych Open, the study is the first to use neuroimaging to demonstrate that a ketogenic diet may improve brain metabolism in individuals with a bipolar disorder diagnosis.
Frequently Asked Questions
Frequently Asked Questions
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© 2024 Metabolic Mind
Guides & Directories
© 2024 Metabolic Mind
© 2024 Metabolic Mind